I’m in perimenopause, my sleep had fallen apart, and magnesium didn’t fix it. Here’s what changed after two months on the She+ jelly sticks by Immunotec, what’s in it, and how it compares to the other menopause supplements out there.
Disclosure: My husband, Brandon, does freelance marketing work for Immunotec, the company that makes She+. I got my first boxes free as an early tester. Nobody at Immunotec reviewed or approved this post, and everything below is my own experience.
- She+ is an apple blueberry jelly stick with black cohosh, red clover, ginger and glucomannan (konjac fiber).
- After about two months, my sleep scores went from constant wake-ups to the 80s and 90s, my energy came back, and my hot flashes eased.
- In Immunotec’s 30-day tester group, 95% noticed changes, and sleep was the most reported improvement (78%).
- Black cohosh and red clover are two of the most studied herbs for menopause, and meta-analyses link both to fewer hot flashes.
- It’s a daily jelly stick, not a pill, and it tastes good enough that I look forward to it.
“I was waking up what looked like every ten minutes all night. Two months on She+, my sleep scores are in the 80s and 90s, I have my energy back, and my hot flashes have calmed way down.”Denise Walsh, perimenopause, She+ tester
Where I was a year ago
My symptoms started creeping in about a year ago. First it was low energy. Then my sleep started going downhill. Then the hot flashes showed up, mostly at night, when I’d wake up sweaty and overheated.
I wear an Oura ring, so I didn’t have to guess how bad my nights were. The sleep graph looked like I was awake every ten minutes, all night long. When you sleep like that, everything else gets harder.
I’m far from alone. A CDC survey of women aged 40 to 59 found that 56% of women in perimenopause sleep less than 7 hours a night, and nearly a third have trouble staying asleep four or more nights a week (CDC NCHS, 2017).
What I tried first
Magnesium was my first move, because it’s what everyone recommends for sleep. It didn’t really help me. That’s not a knock on magnesium. It works for some women, and the research on it for hot flashes is thin either way. It just wasn’t my answer.
What She+ actually is
| Format | Squeezable jelly stick, 20 g each, 20 sticks per box |
|---|---|
| How you take it | One stick a day, any time of day |
| Flavor | Apple blueberry |
| Key ingredients | Black cohosh extract, red clover extract, ginger extract, glucomannan (konjac fiber), apple and blueberry concentrate |
| Free of | Added sugar, gluten, dairy, soy, artificial colors and flavors. Vegan. |
| Made by | Immunotec, headquartered in The Woodlands, Texas. Manufactured in South Korea. |
| Price | About $44 a box on subscription ($59 retail) |
The format is the first thing you notice. It isn’t a pill or a gummy. You squeeze it straight from the stick. I love the taste. It’s apple blueberry, and it’s honestly something I look forward to.
What changed for me
Sleep
This was the big one. My Oura sleep scores went from constant wake-ups to regularly landing in the 80s and 90s.
Energy
My energy came back, and I think that’s mostly because I’m sleeping again.
Hot flashes
They’ve reduced a lot. They’re nowhere near what they were.
Every woman is different, so I also looked at what other women reported and what the research says about the ingredients.
What other women in the first test group reported
Immunotec ran a 30-day product experience with women using She+ before launch. Their results line up with mine: sleep was the biggest change.
Share of participants reporting improvement in each area. Overall, 95% reported noticing changes and 59% noticed changes in the first week. Source: Immunotec 30-day consumer product experience. Self-reported outcomes, not clinical endpoints. Individual results vary.
“The biggest difference I’ve noticed is with the night sweats. I used to wake up with them almost every night, and since I started taking the product, I haven’t had a single one.”Stephanie T., She+ tester. Individual results vary.
“Night sweats went from 5 to only 1 or 2, and sometimes none at all, but the most incredible thing is that I’m sleeping 7 to 8 hours straight!”Claudia J., She+ tester. Individual results vary.
“I sleep deeply and have lots of energy. I’ve noticed I’m not getting irritated so easily anymore.”Silvia V., She+ tester, after about 20 days. Individual results vary.
What the research says about the ingredients
She+ is built around two of the most researched herbs for menopause, plus ginger and a gentle fiber. Here’s what the studies show.
Black cohosh
Most studiedThe most studied herb for menopause, used by women for generations. A 2023 meta-analysis of 22 studies and more than 2,300 women found improvements in hot flashes and in overall menopause symptoms compared with placebo (Menopause, 2023).
On sleep, one small trial found women taking it spent about 16% less time awake after falling asleep than women on placebo (Climacteric, 2015).
Red clover
Clinically studiedContains isoflavones, plant compounds with a weak estrogen-like effect. A 2021 meta-analysis found about 1.7 fewer hot flashes a day compared with placebo, mostly in women having five or more a day (Nutrients, 2021). A 2026 analysis of nine trials confirmed a significant drop in hot flash frequency (EJOG, 2026).
Ginger
Digestive comfortGinger is one of the best-studied plants around. Research supports it for nausea and period cramps, and it’s widely studied for its anti-inflammatory and antioxidant properties (NCCIH). In She+, it supports digestive comfort.
Glucomannan
FiberA soluble fiber from konjac root, and part of what gives the jelly its texture. It’s known for supporting digestion and helping you feel full.
If your symptoms are severe, it’s always worth talking with your doctor about all of your options.
How She+ compares
| Product | Main ingredients | Format | Price |
|---|---|---|---|
| She+ | Black cohosh, red clover, ginger, glucomannan | Jelly stick | $44 a box on subscription |
| Remifemin | Black cohosh extract | Tablet, twice a day | About $14 a month |
| Estroven Complete | Rhapontic rhubarb root | Caplet | About $20 a month |
| Amberen | Proprietary “succinate” blend | Capsule | About $26 a month |
| Bonafide Relizen | Swedish flower pollen | Tablet | $42 to $58 a month |
Competitor prices checked November 2026 from brand sites and major retailers. They change often.
The difference that stood out to me: every other option is a pill or a gummy, and none of the big brands combines black cohosh and red clover. If you hate swallowing pills, the jelly format is a real plus.
Who should talk to a doctor first
- Liver problems. Black cohosh has been linked to rare cases of liver injury. A cause hasn’t been proven, but stop and call your doctor if you notice yellowing skin, dark urine or stomach pain (NIH).
- Breast or uterine cancer history. Safety of black cohosh and red clover isn’t settled for hormone-sensitive cancers (NCCIH).
- Blood thinners. Ginger may raise bleeding risk with warfarin (BJCP, 2021).
- Pregnancy or breastfeeding. Black cohosh and red clover aren’t considered safe.
- Trouble swallowing. Glucomannan swells with liquid, so have a glass of water with it (Health Canada).
My verdict
For me, She+ has been worth it. The sleep change alone made a huge difference in how I feel day to day, and I actually enjoy taking it. If sleep, night sweats or low energy are wearing you down, I think it’s absolutely worth a try.
Frequently asked questions
Is She+ hormone replacement therapy?
No. She+ isn’t hormone replacement therapy (HRT). It’s a daily supplement made with plant extracts, including black cohosh and red clover.
How long does She+ take to work?
In Immunotec’s 30-day test group, 59% noticed changes within the first week. For me, the biggest change was sleep.
Does She+ help with hot flashes?
Mine reduced a lot. Black cohosh and red clover are the two herbs most studied for hot flashes, and night sweats were one of the improvements testers reported most often.
Can I take She+ with hormone therapy or other medications?
Ask your doctor or pharmacist first, especially if you take blood thinners, have liver problems, or have a history of hormone-sensitive cancer.
What does She+ taste like?
Apple blueberry, with a soft jelly texture. It isn’t chalky and there’s no pill to swallow.
Is the She+ by Immunotec the same as SHE+ by Fisher?
No. SHE+ by Fisher is a separate European supplement line. This review is about She+ by Immunotec, the jelly stick launched in the US in October 2026.
Sources
- Black cohosh extracts in women with menopausal symptoms: an updated pairwise meta-analysis. Menopause, 2023. PubMed
- Black cohosh improves objective sleep in postmenopausal women with sleep disturbance. Climacteric, 2015. PubMed
- Clinical meaningfulness of red clover extract to relieve hot flushes. Nutrients, 2021. PubMed
- Effectiveness of red clover on hot flashes: a GRADE-assessed meta-analysis. Eur J Obstet Gynecol Reprod Biol, 2026. PubMed
- Ginger. National Center for Complementary and Integrative Health. NCCIH
- Sleep duration and quality among women aged 40 to 59, by menopausal status. CDC NCHS Data Brief 286, 2017. CDC
- Black cohosh fact sheet for health professionals. NIH Office of Dietary Supplements. NIH ODS
- Health Canada advisory on glucomannan products, 2010. Health Canada
Denise Walsh
Michigan woman in perimenopause, writing about what’s actually helped her sleep, energy and hot flashes.
Jesse Ovlasuk, RN
ICU registered nurse in Grand Rapids. Reviews every post for medical accuracy and safety.
This article reflects one person’s experience and is for general information only. It is not medical advice. Talk with your healthcare provider before starting any supplement. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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